Vadadustat Synthesis, The present invention discloses a method for synthesizing the Vadadustat. In this method, a Chronic kidney disease is a degenerative disorder affecting millions worldwide, often leading to complications such as anemia. Vadadustat is an erythropoiesis-stimulating 摘要： 本发明公开了一种Vadadustat的合成方法. Also described are Vadadustat co-crystals and processes for the preparation thereof. 该方法3,5二氯2吡啶甲酸与甘氨酸甲酯盐酸盐进行缩合反应;将得到的N Download Citation | Robust RP‐HPLC Method for Vadadustat: Development, Validation, Stability, and Green Metrics | Chronic kidney disease is a degenerative disorder affecting millions worldwide A novel and scalable process is developed for the industrial synthesis of vadadustat. Vadadustat, a hypoxia-inducible factor prolyl hydroxylase Introduction: The goal of this study is to provide a comprehensive review of physicochemical and pharmacological properties, including pharmacokinetics and pharmacodynamics parameters, The present invention relates to a novel crystalline compound of Vadadustat, to processes for its preparation, to pharmaceutical compositions containing it and to its use in therapy. Described is a process for the preparation of crystalline Form C of Vadadustat. 21 رجب 1442 بعد الهجرة 24 ذو القعدة 1446 بعد الهجرة Synthesis of Vadadustat Vadadustat is used as raw material of boronic acid and is prepared by coupling, substitution and hydrolysis reactions. Download scientific diagram | (a) The reaction network graph of 2000 retrosynthesis pathways of vadadustat 77 generated from ASKCOS. 1%.